NSAIDs such as ibprophane,Tylenol , ect.. are possibly the most most commonly used drugs on the market. Although these things do work and can be useful, they can potentially cause gastrointestinal issues,kidney, and liver damage. One additional thing that is often forgotten is that we can be come resistant to their effects, therefore the dose over time must be increased to get the desired results. One good rule of thumb is to use them when the doctor deems them acceptable, however its very important to not abuse them by using them for every little ache and pain you have. One thing you should not use them for is muscle soreness. Muscle soreness can be much better dealt with by other therapeutic modalities such as ice, heat, nutrition, and fish oil. Here is a great little article discussing the benefit of fish oil over NSAIDS.